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23andMe, Ancestry and other genotyping services
23andMe offers genotyping services. Discuss genotyping services like Ancestry.com, etc, in this forum. Remember that genotyping services is NOT genome sequencing. See the "Genome sequencing" forum for discussions about genome sequencing.
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1 month, 2 weeks ago
lalo233
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A Plan to Study Your Health
First, you want to get advice on your options for direct-to-consumer omics tests like genome sequencing (e.g. Veritas) or microbiome testing (e.g. Thryve). After you do your test, you will need help to study and validate your omics results. Study Planning involves planning how to study the data with either a statistical test or a data mining study. The plan should involve some Data Management which involves formatting and cleaning data, annotating it with standard terms from a standard vocabulary, and storing it in a database or spreadsheet program.
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3 weeks, 4 days ago
lisamark
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Epigenomics: How your genes get switched on or off
Epigenomics is the study of the complete set of epigenetic modifications on the genetic material of a cell, known as the epigenome. Epigenetic modifications affect which gene is turned on or off. They are reversible modifications on a cell’s DNA or histones that affect gene expression without altering the DNA sequence.
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5 years, 1 month ago
alex
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General Omics Topics
The Omics Forum invites discussions on the best strategies to generate your omics data through Direct-To-Consumer testing providers, or to collect your own health data from doctors or from wearables and sensors, analyze and understand the data, store it securely, and monetize it by participating in programs or using technologies that connect you to the scientific research community and the pharma industry to help develop new medical treatment and better, healthier lives for all.
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2 weeks ago
johnpeterr
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Genome Sequencing
Genome Sequencing is the technology that sequences the whole genome. 23andMe only genotypes certain single nucleotide polymorphisms (SNPs), i.e. single positions, or about half a million of the 3 billion base pairs. Veritas and Nebula are at the forefront of direct-to-consumer genome sequencing. Both Nebula and Veritas were cofounded by MIT professor and “godfather” of the Human Genome Project, George Church.
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5 years, 1 month ago
alex
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Gut-Brain Axis
The gut–brain axis is the biochemical signaling that takes place between the gastrointestinal tract (GI tract) and the central nervous system (CNS) . The interplay of the Gut-Brain axis in health and disease can be studied through omics research.
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5 years, 2 months ago
Leonard_B
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Metabolomics: All the metabolites inside you
Metabolomics is the scientific study of chemical processes and involves the comprehensive detection and identification of metabolites among them sugars, organic acids, amino acids, hormones, neurotransmitters. The metabolome represents the collection of all metabolites in a biological cell, tissue, organ or organism, which are the end products of cellular processes and reveals a much more complete picture of the metabolic state of a person that the current blood work tests ordered by physicians during a regular checkup .
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5 years, 2 months ago
markus
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Microbiome Tests, Metagenomics and Metatranscriptomics
Microbiome tests are offered by Thryve, Viome, DayTwo, and American Gut, and measure all the microbes on or inside your body. Microbial composition in your gut has been shown to be linked to diet, health, brain functioning, and even moods. Metagenomics is the study of microbial communities sampled directly from their natural environment (earth, animal/human tissues or fluids). Metatranscriptomics is the science that studies gene expression of microbes within natural environments such as our body. Post a topic in this forum to discuss the results of your microbiome test or if you are planning to have a test done and need to compare the options.
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5 years, 6 months ago
patyb
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Model of health: (Epi/Meta)Genome*Exposome=Phenome
Use this forum to discuss the model for human health and well-being: (Epi/Meta)genome*exposome=phenome
Phenomes consist of the physical and biochemical traits of an organism as they change in response to genetic factors ((Epi/Meta)genomics) and environmental and external influences (exposome). Phenome data can involve self-measurement data, such as sensor data, blood test results, among others. Emotions are included in the phenome. They are linked to production of hormones and neurotransmitters which can be measured, and so good and bad emotions can be measured. The exposome can be defined as the measure of all the exposures of an individual in a lifetime and how those exposures relate to health. Exposome data can involve self-measurement data, such as the foods someone eats, the social interactions in one’s life, and environmental influences, among many others. As for the (Epi/Meta)genome, it is a big factor in our health and well-being. Our genome codes how our body reacts to the exposome, while exposure to different environments, foods, situations can modulate or change the pattern of gene expression and our epigenome or metagenome (our microbes population)
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1 year ago
percyholmes95
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Proteomics
The proteome is the entire set of proteins, produced or modified by an organism or system. This varies with time and distinct exposures, or stresses, that a cell or organism undergoes
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2 years, 1 month ago
robertsanborn01